CuO, categorized into the transition metal oxide group, is a p-type, narrow bandgap semiconductor. It has a monoclinic structure and many exciting characteristics: superthermal conductivity, photovoltaic properties, high stability, and antimicrobial activity. Due to such exclusive properties, CuO can be used in many technological fields, for example, active catalysts, gas sensors, high-efficiency thermal conducting material, magnetic recording media with excellent selectivity, or solar cell applications. In addition to some shared properties of metal oxide nanostructures, such as TiO2, ZnO, WO3, and SnO2, CuO nanostructures have other unique magnetic and super-hydrophobic [10] properties. Furthermore, these nanostructures show up-and-coming applications in heterogeneous catalysis in the complete conversion of hydrocarbons into carbon dioxide, enhancement of thermal conductivity of nanofluid, nano energetic materials, and super-hydrophobic surfaces or anode materials for lithium-ion batteries (LIBs). However, this material has only gotten the attention of scientists at the right level recently. Compared with other oxides of transition metals such as Fe2O3, TiO2, and ZnO, only a few reports have described the synthesis strategies adopted for CuO nanostructures along with the introduction of their related applications. In this paper, we would like to systematically discuss the effect of some factors in the solution-based process on the nanoproducts rather than focus on each synthesis process. Critical comments will be provided for each factor based on our knowledge and related research experience. Some properties and potential applications of CuO nanostructures reported in the literature will also be presented. This review aims to discuss the synthesis of CuO nanostructures critically. The potentials of CuO nanostructures as functional components for fabricating micro/nanodevices are also evaluated and highlighted. If you are looking for high quality, high purity, and cost-effective Copper Oxide, or if you require the latest price of Copper Oxide, please feel free to email contact mis-asia.